Whipple disease without joint involvement in a patient with chronic diarrhea and HIV seropositive partner: case report

Luis Arthur Brasil Gadelha Farias, Mateus Lavor Lira, Matheus Dias Girão Rocha, Alessandra Marques dos Santos, Terezinha do Menino Jesus Silva Leitão, Evelyne Santana Girão, Jorge Luiz Nobre Rodrigues


Introduction: Whipple’s disease is a rare, infectious disease caused by the bacterium Tropheryma whipplei that affects multiple organs and systems. It is difficult to identifyand frequently presents as a diagnosis of exclusion due existence of conditions causing most prevalent chronic diarrhea, as AIDS and Inflammatory Bowel Disease. Case report: Herein we report the clinical findings of a 38-year-old male patient, married with a HIV seropositive woman, with a four-year course of chronic diarrhea until he received a definitive diagnosis. Treatment was started with a 15-day penicillin G regimen, followed by continued trimethoprim–sulfamethoxazole 80/400mg after hospital discharge up to current days. Conclusion: Currently, the patient remains asymptomatic and has completed clinical remission after two years of treatment.


Whipple’s Disease; Diarrhea; Chronic Disease; Arthritis; Weight Loss

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DOI: http://dx.doi.org/10.12662/2317-3076jhbs.v6i1.1440.p108-112.2018


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Direitos autorais 2017 Journal of Health & Biological Sciences

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