Severe Kala-azar and seric level of IL-6: case reports
DOI:
https://doi.org/10.12662/2317-3076jhbs.v8i1.3035.p1-4.2020Palavras-chave:
Calazar, Interleucina-6, Coinfecção, Hepatite BResumo
Introduction: IL-6 cytokine participates in the inflammatory process of systemic leishmaniasis and elevated levels are associated with active disease. Case reports: Three patients with different age groups and different severity scores, above 4 were reported, and IL-6 plasma concentrations and their association with disease severity were observed. Conclusion: Analysis suggests that only the score, has no sensitivity to classify, among others critically ill patients, those with imminent risk of death. IL-6 concentrations can allow this differentiation, considering that only fatal case, HBV/Leishmania coinfection, presented expressively higher level of the cytokine concentration.
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