Rhino-orbital mucormycosis in a diabetes patient with renal impairment after amphotericin B deoxycholate: the role of amphotericin B lipid-complex treatment

Italo Gustavo Lima Monteiro; Luis Arthur Brasil Gadelha Farias; Ruth Maria Oliveira de Araújo; Licia Borges Pontes

doi:10.12662/2317-3076jhbs.v9i1.3545.p%p.2021

Rhino-orbital mucormycosis in a diabetes patient with renal impairment after amphotericin B deoxycholate: the role of amphotericin B lipid-complex treatment

Autores

Italo Gustavo Lima Monteiro Hospital Universitário Walter Cantídeo (HUWC)
Luis Arthur Brasil Gadelha Farias Faculty of Medicine, Federal University of Ceará (UFC)
Ruth Maria Oliveira de Araújo Hospital Universitário Walter Cantídeo (HUWC)
Licia Borges Pontes Hospital Universitário Walter Cantídeo (HUWC) Centro Universitário Christus (UNICHRISTUS)

DOI:

https://doi.org/10.12662/2317-3076jhbs.v9i1.3545.p%25p.2021

Palavras-chave:

Mucormycosis, Amphotericin B, Liposomal Formulation,  Drug Therapy

Resumo

Introduction: Mucormycosis is an infection caused by the ubiquitous saprophyte fungi with rapid and aggressive progression, especially in immunocompromised patients. Case report: A 57-year-old woman diagnosed with rhino-orbital mucormycosis presented with decreased renal function after treatment with amphotericin B deoxycholate which was discontinued. Renal function improved after amphotericin B lipid-complex, being also treated with itraconazole, and otorhinolaryngological surgery. Conclusion: The use of Amphotericin B deoxycholate may result in adverse effects. In this situation, Amphotericin B lipid formulation is usually the drug of choice.

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Biografia do Autor

Luis Arthur Brasil Gadelha Farias, Faculty of Medicine, Federal University of Ceará (UFC)

Graduando em Medicina pela Universidade Federal do Ceará (UFC), com previsão de conclusão em 2019. Atualmente, encontra-se vinculado à IFMSA- Brazil, onde exerce a função de LVPE- Local Vice- President for external affairs no comitê UFC-Fortaleza. É monitor de Parasitologia Médica na Universidade Federal do Ceará e Membro ativo da Liga de Estudos e Ações em Doenças Infecciosas - LEDI.

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Publicado

2021-06-07

Como Citar

Monteiro IGL, Farias LABG, de Araújo RMO, Pontes LB. Rhino-orbital mucormycosis in a diabetes patient with renal impairment after amphotericin B deoxycholate: the role of amphotericin B lipid-complex treatment. J Health Biol Sci. [Internet]. 7º de junho de 2021 [citado 3º de julho de 2024];9(1):1-4. Disponível em: https://periodicos.unichristus.edu.br/jhbs/article/view/3545