Wernicke-Korsakoff Syndrome associated with hyperemesis gravidarum and fetal death: Case report and literature review

Autores

  • Sâmya Pessoa de Amorim Marinho Hospital Cesar Cals
  • Raquel Viana Furtado Hospital Cesar Cals
  • Paola Lima Lemos Hospital Cesar Cals
  • Jose Walter Correia Hospital Cesar Cals
  • Orivaldo Alves Barbosa Hospital Cesar Cals https://orcid.org/0000-0002-4075-5761

DOI:

https://doi.org/10.12662/2317-3076jhbs.v11i1.4810.p1-5.2023

Palavras-chave:

Wernicke Encephalopathy, Korsakoff Syndrome, Pregnancy, Hyperemesis gravidarum

Resumo

We describe a clinical case of a pregnant patient with hyperemesis gravidarum who progressed to abortion, Wernicke's encephalopathy, and Korsakoff's psychosis, all related to thiamine deficiency. The patient presented symptoms of disorientation, nonspecific limb movements, and fever, initially treated with metronidazole and ceftriaxone for suspected infected abortion. Subsequently, the patient was diagnosed with retained and infected abortion, and thiamine replacement therapy was initiated with an intravenous loading dose of 900 mg/day. During hospitalization, the patient presented with tetraparesis, nystagmus, decreased level of consciousness, anterograde and retrograde amnesia, confabulation, and aphasia. Magnetic resonance imaging showed lesions in the pons, typical of Wernicke's encephalopathy. The patient was empirically treated with acyclovir and ampicillin and showed clinical improvement. The text also provides a brief narrative review of the literature on the topic.

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Biografia do Autor

Sâmya Pessoa de Amorim Marinho, Hospital Cesar Cals

Medica Residente de Clinica Médica - Hospital Cesar Cals

Raquel Viana Furtado, Hospital Cesar Cals

Medica Residente de Clinica Médica - Hospital Cesar Cals

Paola Lima Lemos, Hospital Cesar Cals

Médica Neurologista - Hospital Cesar Cals

Jose Walter Correia, Hospital Cesar Cals

Medico Internista, PhD

Publicado

2023-08-29

Como Citar

1.
Marinho SP de A, Furtado RV, Lemos PL, Correia JW, Barbosa OA. Wernicke-Korsakoff Syndrome associated with hyperemesis gravidarum and fetal death: Case report and literature review. J Health Biol Sci. [Internet]. 29º de agosto de 2023 [citado 22º de dezembro de 2024];11(1):1-5. Disponível em: https://periodicos.unichristus.edu.br/jhbs/article/view/4810