Morphological alterations in endometrium after use of levonorgestrel-releasing intrauterine system: a case report

Authors

  • Francisco das Chagas Medeiros Universidade Federal do Ceará (UFC)
  • Matheus Duarte Pimentel Universidade Federal do Ceará (UFC) https://orcid.org/0000-0001-9833-3943
  • Rodrigo Dias Custódio Universidade Federal do Ceará (UFC)
  • Dalgimar Beserra de Menezes Universidade Federal do Ceará (UFC)

DOI:

https://doi.org/10.12662/2317-3076jhbs.v8i1.2379.p1-4.2020

Keywords:

Endometrium, Morphology, Levonorgestrel

Abstract

Case Report: A 44-year-old patient attended the gynecology service for routine consultation. The patient reported implantation of a levonorgestrel-releasing intrauterine system (LNG-IUS), five years ago. No macroscopic changes were seen in the uterus or in the endometrium cavity during the procedure, but an endometrial biopsy was performed. Histopathological analysis revealed an endometrium with an expanded stroma by pseudo-decidualization and mucoid (mucinous) alterations, forming small puddles of mucin, also presenting with polypoid indentations, ectatic vessels, lymphoid cell foci, including plasma cells and deposits of calcium salts. Conclusion: As the use of this type of contraceptive method becomes more usual, knowledge of LNG-IUS-induced changes becomes increasingly relevant for the assessment of its long-term efficacy and safety.

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Author Biographies

Francisco das Chagas Medeiros, Universidade Federal do Ceará (UFC)

Adjunct Professor, Department of Maternal-Child Health, Faculdade de Medicina, Universidade Federal do Ceará (UFC), Fortaleza, CE, Brazil

Matheus Duarte Pimentel, Universidade Federal do Ceará (UFC)

Medical Student, Faculdade de Medicina, Universidade Federal do Ceará (UFC), Fortaleza, CE, Brazil

Rodrigo Dias Custódio, Universidade Federal do Ceará (UFC)

Medical Student, Faculdade de Medicina, Universidade Federal do Ceará (UFC), Fortaleza, CE, Brazil

Dalgimar Beserra de Menezes, Universidade Federal do Ceará (UFC)

Emeritus Professor, Pathology Department, Faculdade de Medicina, Universidade Federal do Ceará (UFC), Fortaleza, CE, Brazil

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Published

2020-01-03

How to Cite

1.
Medeiros F das C, Pimentel MD, Custódio RD, de Menezes DB. Morphological alterations in endometrium after use of levonorgestrel-releasing intrauterine system: a case report. J Health Biol Sci. [Internet]. 2020 Jan. 3 [cited 2025 Feb. 5];8(1):1-4. Available from: https://periodicos.unichristus.edu.br/jhbs/article/view/2379

Issue

Vol. 8 No. 1 (2020): Journal of Health and Biological Sciences

Section

Case Report

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