Prospecting the antibacterial activity of Vachellia farnesiana (L.) against strains of Staphylococcus aureus and Pseudomonas aeruginosa

Abstract

Objective: this study aimed to determine the antibacterial potential of the ethanolic extract of Vachellia farnesiana against strains of Staphylococcus aureus ATCC 25923 and Pseudomonas aeruginosa (ATCC 10145). Method: to analyze the antimicrobial activity, Antimicrobial Susceptibility Tests (AST) were performed using crude ethanolic extracts from the flowers, branches, roots, and pods of the plant V. farnesiana (L.) Wight & Arn. For these tests, a broth microdilution method was used to determine the minimum inhibitory concentration (MIC), and plating was employed to assess the minimum bactericidal concentration (MBC). Results: the growth reduction results were statistically significant for both strains compared to the control, especially for the roots’ ethanolic extract. However, S. aureus was more sensitive than P. aeruginosa. The antimicrobial effect shown by the crude extract was bacteriostatic. Conclusion: thus, given the antibacterial potential V. farnesiana demonstrated, it is necessary to determine which biological compost of the extract has bacteriostatic activity and, in addition, to expand the research against other bacterial species of medical interest.