Anxiolytic and antidepressant effects of cannabidiol: a systematic review

Autores

  • José Eduardo Ribeiro Honório Júnior Christus University Center https://orcid.org/0000-0001-8320-8525
  • Jessica Rodrigues de Morais Barriga Biomedical formed by the Centro Universitário Christus (UNICHRISTUS), Campus Parque Ecológico, Fortaleza, Ceará, Brazil.
  • Dara da Silva Mesquita Master's Student of the Master's Course in Translational Medicine at the Federal University of Ceará (UFC), Campus Porangabuçu, Fortaleza, Ceará, Brazil.
  • Joel Porfírio Pinto Professor of the Psychology Course at the University of Fortaleza (UNIFOR) and psychologist of the hospital of mental health Professor Frota Pinto Fortaleza, Ceará, Brazil https://orcid.org/0000-0001-6084-7818

DOI:

https://doi.org/10.12662/2317-3076jhbs.v9i1.3366.p1-7.2021

Palavras-chave:

Cannabis, Cannabidiol, Anxiolytic, Antidepressant

Resumo

Objetctive: Realize a systematic review on articles about cannabidiol (CBD) as an anxiolytic and antidepressant drug. Methodology: A systematic review in PubMed, Science Direct and PsycINFO databases taking into consideration articles published in English and Portuguese from 2008 to 2018 with animal experimentation. Results: Eleven articles with experimental studies on animals were included. All studies exhibited anxiolytic and antidepressant activities after CBD use. Conclusion: It was proven by several experiments the anxiolytic and antidepressant activity of CBD, however there is still a need of more preclinicals and clinicals studies to elucidate its mechanisms.

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Publicado

2021-04-06

Edição

v. 9 n. 1 (2021): Journal of Health and Biological Sciences

Seção

Artigos de Revisão

Licença

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Creative Commons License

Este artigo está licenciada sob uma licença Creative Commons - Atribuição-Não Comercial- Sem Derivações 4.0 Internacional